FRI proudly celebrates its 70th anniversary this year! This milestone marks seven decades of advancing science and improving lives. Founded in 1955 in Baltimore, Maryland as “Friends of Psychiatric Research,” FRI began as a small community-based organization focused on improving the quality of care of individuals with mental illness. In the ensuing years, FRI broadened its scope to address the intersecting challenges of substance use, health, and involvement in the criminal legal system. For seven decades, FRI investigators and staff have conducted groundbreaking work on some of the nation’s most vexing health and social problems. This work has helped to shape scientific understanding, clinical practice, and policy in the areas of addiction, mental health, HIV/AIDS, and criminal justice reform.