Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants: A Phase 3 Randomized Controlled Trial.

Fava, M., Stahl, S. M., Pani, L., De Martin, S., Cutler, A. J., Maletic, V., Gorodetzky, C. W., Vocci, F. J., Sapienza, F. L., Kosten, T. R., Kröger, C., Champasa, P., O’Gorman, C., Guidetti, C., Alimonti, A., Comai, S., Mattarei, A., Folli, F., Bushnell, D., Traversa, S., … Pappagallo, M. (2024). Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants: A Phase 3 Randomized Controlled Trial. The Journal of clinical psychiatry, 85 (3), 24m15265. https://doi.org/10.4088/JCP.24m15265.